Not known Factual Statements About sodium pentobarbital
Not known Factual Statements About sodium pentobarbital
Blog Article
pentobarbital will lower the level or effect of ziprasidone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Significance Unidentified.
pentobarbital will lower the extent or effect of alosetron by impacting hepatic enzyme CYP2C9/ten metabolism. Slight/Importance Mysterious.
pentobarbital will decrease the extent or effect of finasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Importance Unidentified.
buprenorphine, very long-performing injection and pentobarbital both raise sedation. Stay away from or Use Alternate Drug. Limit use to individuals for whom alternative remedy selections are inadequate
Phenytoin, sodium valproate, valproic acid: The effect of barbiturates over the metabolism of phenytoin appears to become variable. Some investigators report an accelerating effect, even though others report no effect. As the effect of barbiturates about the metabolism of phenytoin is not really predictable, phenytoin and barbiturate blood levels must be monitored additional usually if these drugs are supplied concurrently.
pentobarbital will lower the extent or effect of pantoprazole by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown.
Check Closely (one)pentobarbital will decrease the extent or effect of hydrocodone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep an eye on Carefully. Caution when discontinuing CYP3A4 inducers that are coadministered with hydrocodone; plasma concentrations of hydrocodone may perhaps boost and may result in possibly fatal respiratory depressionSerious - Use Alternative (one)hydrocodone, pentobarbital.
Nursing mothers: Warning needs to be exercised every time a barbiturate is administered to a nursing woman since small quantities of barbiturates are excreted from the milk.
pentobarbital will reduce the level or effect of nitrendipine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Importance Unknown.
A lot of pharmaceutical companies have stopped supplying drugs towards the government for executions, but Demise penalty opponents say there are methods for the government to uncover workarounds.
pentobarbital will decrease the level or effect of fosaprepitant by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.
pentobarbital will lessen the level or effect of quinidine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
This mechanism is probably with the read more induction of hepatic microsomal enzymes that metabolize the antibiotic. If phenobarbital and doxycycline are administered concurrently, the clinical response to doxycycline should be monitored closely.
The sodium salt occurs to be a white, a little bitter powder and that is freely soluble in water and alcohol but nearly insoluble in benzene and ether.